Dr. Yuji Tokuanga, Associate Professor
Department of Material Science and Engineering
Faculty of Engineering
Fukui University
Bunkyo, Fukui 910-8507, Japan
Phone and Fax +81-776-27-8611
E-mail:tokunaga@matse.fukui-u.ac.jp

Resaerch interests; Molecular Recognition, Self-Assembly, Self-Organization, Molecular information

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Yuji Tokunaga was born in Tokyo (April 19, 1965), and he holds a Ph. D. at Tohoku University.
He spent 1991-1993 working at Tanabe Pharmaceutical Co., Ltd. He returned back to Tohoku University as a research assistant in 1993. In 1996, Dr. Y. Tokunaga moved to the USA, where he worked as post-doc in the group of Prof. Julius Rebek, Jr. at The Scripps research Institute.
In 1997, Dr. Y Tokunaga moved back to Japan, he worked for Otsuka Pharmaceutical Co., Ltd. in Akoh.
Currently, Dr. Y Tokunaga is an Associate Professor within Dr. Toshihiro Seo laboratory at Department of Material Science and Engineering, Fukui University.

Publications

  1. "A Simple and Enantioselective Synthesis of (+)-Albicanol", J. Chem. Soc.,Chem. Commun., 1989, 1093-1094. K. Shishido, Y. Tokunaga, N. Ohmachi, K. Hiroya, K. Fukumoto, and T. Kametani.
  2. "Alkoxide-mediated Oxidative Ring Expansion of Benzocyclobutenes. A New Route to 3,4-Dihydroisocoumarines", Heterocycles, 1990, 30, 253-256. K. Shishido, K. Hiroya, A. Yamashita, Y. Tokunaga, and K. Fukumoto.
  3. "A Novel Synthetic Approach to Steroids via Intramolecular 1,3-Dipolar Cycloaddition. A Highly Stereocontrolled Synthesis of Testosterone", J. Org. Chem., 1990, 55, 4497-4498. M. Ihara, Y. Tokunaga, and K. Fukumoto.
  4. "Total Synthesis of (+)-Albicanol and (+)-Albicanyl Acetate via a Highly Diastereoselective Intramolecular [3+2]Cycloaddition", J. Chem. Soc., Perkin Trans. I, 1990, 2481-2486. K. Shishido, Y. Tokunaga, N. Ohmachi, K. Hiroya, and K. Fukumoto.
  5. "Stereoselective Synthesis of (+)-Testosterone via Intramolecular 1,3-Dipolar Cycloaddition of Nitrile Oxide", Tetrahedron, 1991, 47, 6635-6648. M. Ihara, Y. Tokunaga, N. Taniguchi, and K. Fukumoto.
  6. "A Novel Approach to Angular Triquinanes via Intramolecular 1,3-Dipolar Cycloaddition of Nitrile Oxide", J. Org. Chem., 1991, 56, 5281-5285. M. Ihara, Y. Tokunaga, N. Taniguchi, and K. Fukumoto.
  7. "Asymmetric Total Synthesis of Tacamonine (Pseudovincamone I) via Radical Cyclization", J. Org. Chem., 1994, 59, 5317-5323. M. Ihara, F. Setsu, M. Shohda, N. Taniguchi, Y. Tokunaga, and K. Fukumoto.
  8. "Modification of the Julia Alkenation Using SmI2-HMPA", Synlett, 1994, 859-860. M. Ihara, S. Suzuki, T. Taniguchi, Y. Tokunaga, and K. Fukumoto.
  9. "Stereoselective Formation of Three Carbon-Carbon Bonds by Cascade Reaction with Enolate Anion: Synthesis of Tricyclo[6.2.2.01,6]dodecan and Tricyclo[5.3.1.03,8]undecane Derivatives", J. Org. Chem., 1994, 59, 6008-6013. M. Ihara, K. Makita, Y. Tokunaga, and K. Fukumoto.
  10. "Ring Construction of Cyclobutanes and a Novel Cascade Reaction: Application to Synthesis of (})-Anthoplalone and (})-Lepidozene", J. Org. Chem., 1994, 59, 8092-8100. M. Ihara, T, Taniguchi, Y. Tokunaga, and K. Fukumoto.
  11. "Indirect Electroreductive Cyclization for Syntheses of Key Intermediates of Several Indole and Ipecac Alkaloids", Chem. Pharm. Bull., 1995, 43, 362-364. M. Ihara, F. Setsu, Y. Tokunaga, K. Fukumoto, Y. Kashiwagi, and T. Osa.
  12. "Unexpected Stereoselectivity of Intramolecular 1,3-Dipolar Cycloaddition Caused by the Presence of Fluorine Atom", Heterocycles, 1995, 40, 97-100. M. Ihara, T. Kawabuchi, Y. Tokunaga, and K. Fukumoto.
  13. "A Simple Total Synthesis of (})-Spirojatamol and (})-Erythrodiene via Intramolecular 1,3-Dipolar Cycloaddition", J. Chem. Soc., Chem. Commun., 1995, 955-956. Y. Tokunaga, M. Yagihashi, M. Ihara, and K. Fukumoto.
  14. "The Synthesis of 1b-Fluorocarbapenem Derivative", Heterocycles, 1996, 42, 437-443. M. Ihara, K. Satoh, Y. Ihara, N. Taniguchi, Y. Tokunaga, M. Takemura, and K. Fukumoto.
  15. "Construction of Polycyclic Ring Systems Fused to Cyclobutane by Cascade Reactions of Formyl a,b-Unsaturated Esters", Synthesis, 1995, 1405-1410, M. Ihara, T. Taniguchi, Y. Tokunaga, and K. Fukumoto.
  16. "Stereocontrolled Intramolecular Michael-Aldol Reaction Mediated with Bu2BOTf and (TMS)2NH", Tetrahedron Lett., 1995, 36, 8071-8074. M. Ihara, T. Taniguchi, M. Yamada, Y. Tokunaga, and K. Fukumoto.
  17. "Stereocontrolled Synthesis of Indolo[2,3-a]quinolizines by Intramolecular Double Michael Reaction: Proof for Stepwise Mechanism", J. Chem. Soc., Chem. Commun., 1995, 2085-2086. M. Ihara, Y. Ishida, Y. Tokunaga, C. Kabuto, and K. Fukumoto.
  18. "Preparation of Chiral Building Blocks for Synthesis of Aconitium Alkaloids", Tetrahedron: Asymmetry, 1995, 6, 2053-2058. M. Ihara, M. Suzuki, A. Hirabayashi, Y. Tokunaga, and K. Fukumoto.
  19. "Preparation of Olefins and Acetylenes via Reductive Elimination with SmI2-HMPA", Tetrahedron, 1995, 51, 9873-9890. M. Ihara, S. Suzuki, T. Taniguchi, Y. Tokunaga, and K. Fukumoto.
  20. "Assembly of Bicyclo[2.2.1]heptane Derivatives by Two Types of Domino Reaction", J. Chem. Soc., Perkin Trans. 1, 1995, 2811-2812. M. Ihara, S. Suzuki, Y. Tokunaga, and K. Fukumoto.
  21. "Enantiocontrolled Synthesis of Chiral Propane-1,3-diol Derivatives Possessing Fluorinated Quaternary Stereogenic centers", Tetrahedron; Asymmetry, 1994, 5, 1041-1051. M. Ihara, T. Kawabuchi, Y. Tokunaga, and K. Fukumoto.
  22. "Stereoselective Construction of the Diterpene Part of Indole Alkaloids, Radarins, by Way of Intramolecular Diels-Alder Reaction", J. Org. Chem., 1995, 60, 5560-5566. M. Ihara, A. Katsumata, M. Egashira, S. Suzuki, Y. Tokunaga, and K. Fukumoto.
  23. "Synthesis of Six-Membered Compounds by Environmentally Friendly Cyclization Using Indirect Electrolysis", J. Org. Chem., 1996, 61, 677-684. M. Ihara, A. Katsumata, F. Setsu, Y. Tokunaga, and K. Fukumoto.
  24. "Silver(I) Salt Promoted Generation of Nitrile Oxides from Hydroximoly Chlorides", Heterocycles, 1996, 43, 1771-1775. Y. Tokunaga, M. Ihara, and K. Fukumoto.
  25. "1,3-Dipolar Cycloaddition of 1-Carboxy Nitrone: Different Stereoselectivity Caused by Salt Effect", Tetrahedron Lett., 1996, 37, 6157-6160. Y. Tokunaga, M. Ihara, K. Fukumoto.
  26. "Facile Construction of the Bicyclo[6.4.0]dodecane System by the Intramolecular Michael Addition of Sulfonyl Carbanion", J. Chem. Soc., Chem. Commun., 1996, 1801-1802. M. Ihara, S. Suzuki, Y. Tokunaga, H. Takeshita, and K. Fukumoto.
  27. "Stereoselective Construction of Copaborneol and Longiborneol Frameworks by Intramolecular Double Michael Reaction" J. Org. Chem., 1996, 61, 6416-6421. M. Ihara, K. Makita, Y. Fujiwara, Y. Tokunaga, and K. Fukumoto.
  28. "Facile Construction of Spirobicyclic Skeletons by Intramolecular Aldol Reaction: Simple Formal Synthesis of (})-Spirojatamol and (})-Erythrodiene" J. Chem. Soc., Chem. Commun., 1997, 189-190. Y. Tokunaga, M. Yagihashi, M. Ihara, K. Fukumoto.
  29. "Synthesis of Benzo[a]quinololizines by the Intramolecular Double Michael Reaction Under Three Different Conditions", Heterocycles, 1997, 44, 531-536. M. Ihara, M. Yamada, Y. Ishida, Y. Tokunaga, and K. Fukumoto.
  30. "A Mild Oxidative Transformation of Nitro Compounds into Ketone by Tetrapropylammonium Perruthenate", J. Chem. Soc., Perkin Trans.1, 1997, 207-209. Y. Tokunaga, M. Ihara, and K. Fukumoto.
  31. "Influence of a 2-Fluoro Substituent on Diastereoselectivity in the 1,3-Dipolar Cycloaddition of Nitrones", J. Chem. Soc., Perkin Trans.1, 1997, 3043-3052. M. Ihara, Y. Tanaka, N. Takahashi, Y. Tokunaga, and K. Fukumoto.
  32. "Solvation and the Synthesis of Self-Assembled Capsules", Angew. Chem., Int. Ed. Engl. 1997, 36, 2656-2659. Y. Tokunaga, D. M. Rudkevich and J. Rebek, Jr.
  33. "Chiral Capsules. 1. Softballs with Asymmetric Surfaces Bind Camphor Derivatives", J. Am. Chem. Soc., 1998, 120, 66-69. Y. Tokunaga and J. Rebek, Jr.
  34. "Solvent Contrrols Synthesis and Properties of Supramolecular Structures ", Chem. Eur. J., 1998, 4, 1449-1457. Y. Tokunaga, D. M. Rudkevich, J. Santamaria, G. Hilmersson, and J. Rebek, Jr.
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